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[DOI] [PMC free article] [PubMed] [Google Scholar] Flahou B

Is LipoQ10 nutritionally complete

Targeting mitochondrial structure sensitizes acute myeloid leukemia to venetoclax treatment

Publications Publications Shade C

Alteration of several metabolic enzymes and pathways that affect KG abundance and KGDD activity have been reported in cancer, such as mutations of the genes encoding isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2), changes in glutaminolysis that deplete KG, and alterations in fumarate hydratase and succinate dehydrogenase that inhibit KGDD activity 11